8 new oncology trials approved in Europe


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8 new oncology trials approved in Europe

Good morning, here is a concise selection of oncology and haematology trials recently authorised in Europe.

Breast density reduction with linzagolix or bilastine in premenopausal women at high risk of breast cancer: a phase II clinical trial.

Sponsor: Consorci Mar Parc De Salut De Barcelona Phase: 2

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A phase 2 study to assess efficacy of induction Enfortumab Vedotin plus Pembrolizumab using a response-adapted approach to spare the bladder: FIDELIO

Sponsor: Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Stichting Phase: 2

Interested in offering this trial to suitable patients?

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ctDNA-guided Enfortumab Vedotin plus Pembrolizumab in Untreated Patients with Advanced Urothelial Carcinoma. The FUTURE Study

Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS Phase: 4

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Hepatic arterial infusion versus intravenous oxaliplatin in a safety, feasibility and pharmacokinetic study of liver-dominant malignancies – ARTEMIS OXYS-I trial

Sponsor: Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC) Phase: 1

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LIGHTBEAM-U01 Substudy 01E: A Phase 2 Substudy to Evaluate the Safety and Efficacy of Belzutifan in Participants With Solid Tumors

Sponsor: Merck Sharp & Dohme LLC Phase: 2

Not accepting new sites

A Phase III, Open-label, Multicentre, Randomised Study Comparing Consolidation Treatment with AZD0120, an Autologous Dual Targeting Chimeric Antigen Receptor T-cell (CAR-T) Therapy Directed Against BCMA and CD19, versus Autologous Stem Cell Transplant (ASCT) in Participants with Newly Diagnosed Multiple Myeloma who are Transplant Eligible (TE NDMM) (DURGA-6)

Sponsor: AstraZeneca AB Phase: 3

Not accepting new sites

A Phase Ib/II, open-label, safety and tolerability trial of obrixtamig in combination with ZL-1310 in patients with poorly differentiated NEC

Sponsor: Boehringer Ingelheim International GmbH Phase: 1, 2

Not accepting new sites

First-in-human study of ATX-898 as monotherapy and in combination with other anti-neoplastic agents, in participants with advanced solid tumors

Sponsor: Antares Therapeutics Inc. Phase: 1, 2

Not accepting new sites

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