9 new oncology trials approved in Europe


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9 new oncology trials approved in Europe

Good morning, here is a concise selection of oncology and haematology trials and investigator opportunities in Europe.

VIKTORIA-2: A Randomized, Open-Label, Phase 3 Study Evaluating Efficacy and Safety of Gedatolisib with Endocrine Therapy and Palbociclib vs Endocrine Therapy and Ribociclib as First-Line Treatment in Patients With HR-Positive and HER2-Negative Advanced Breast Cancer

Sponsor: Celcuity Inc. Phase: 3

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A Phase 1/2 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of VRN110755 in Patients with Epidermal Growth Factor Receptor (EGFR) Mutant Non-small Cell Lung Cancer (NSCLC)

Sponsor: Voronoi Inc. Phase: 1, 2

Interested in offering this trial to suitable patients?

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Phase III ASP2138 with chemotherapy and pembrolizumab in CLDN18.2-positive HER2-negative advanced gastric or GEJ cancer

Sponsor: Astellas Pharma Global Development Inc. Phase: 3

Interested in offering this trial to suitable patients?

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A Phase 1/2 Open-label Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Preliminary Anti-tumor Activity of ARV-6723 Administered as Monotherapy and in Combination with Pembrolizumab in Participants with Advanced Solid Tumors

Sponsor: Arvinas Operations Inc. Phase: 1, 2

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A Phase 2, Open-label Study of VS-7375, an Oral KRAS G12D (ON/OFF) Inhibitor, in Patients with Previously Treated, Advanced KRAS G12D-Mutated Non-Small Cell Lung Cancer (TARGET-D 202)

Sponsor: Verastem Inc. Phase: 2

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A Randomized, Open-Label, Multicenter, Phase 3 Study to Investigate Mocertatug Rezetecan with Bevacizumab Compared with Platinum Doublet with Bevacizumab in Participants with Platinum-Sensitive Ovarian Cancer

Sponsor: Glaxosmithkline Research & Development Limited Phase: 3

Not accepting new sites

A Phase Ib/II, open-label, safety and tolerability trial of intravenous obrixtamig in combination with pumitamig and standard of care (carboplatin, etoposide) in patients with extensive stage small cell lung carcinoma.

Sponsor: Boehringer Ingelheim International GmbH Phase: 1, 2

Not accepting new sites

A Study of RO7821657 in Participants with Solid Tumors

Sponsor: F. Hoffmann-La Roche AG Phase:

Not accepting new sites

A Randomised, Double‑Blind, Placebo‑Controlled, 2‑Cohort, Phase III Study of Saruparib Combined with Physician’s Choice of Androgen Receptor Pathway Inhibitor in Patients With Metastatic Hormone‑Sensitive Prostate Cancer, Previously Treated With Docetaxel or PSMA‑directed 177Lutetium‑Containing Therapy Without Disease Progression, and With Prostate‑Specific Antigen ≥ 0.2 ng/mL: EvoPAR Prostate‑05

Sponsor: AstraZeneca AB Phase: 3

Not accepting new sites

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