11 new oncology trials approved in Europe


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11 new oncology trials approved in Europe

Good morning, here is a concise selection of oncology and haematology trials and investigator opportunities in Europe.

A Study of LY4152199 in Participants With Previously Treated B-cell Malignancies (BAF_FRontier-1)

Sponsor: Eli Lilly & Co. Phase:

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A multicentre open-label phase I/Ib trial of melanoma-specific peptide vaccination (UniCanVax) combined with nivolumab in checkpoint blockade-refractory stage III/IV melanoma

Sponsor: Humanitas Mirasole S.p.A. Phase: 1

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A Phase 2, Randomized, Open-label Study of VVD-133214 with Pembrolizumab versus Pembrolizumab Monotherapy in Advanced MSI-H/dMMR Colorectal Adenocarcinoma

Sponsor: Vividion Therapeutics Inc. Phase: 2

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Use of Dapagliflozin in Primary Prevention of Cardiotoxicity of Anthracycline Chemotherapy in Breast Cancer Patients (ALPACA)

Sponsor: Institute Of Oncology Ljubljana Phase: 2

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ORION-1: A phase 1/2, first-in-human study to assess the safety, tolerability, pharmacokinetics, pharmacodynamics, and antitumor activity of AVZO-023 as a single agent, and in combination with AVZO-021 and/or endocrine therapy in patients with advanced solid tumors

Sponsor: Avenzo Therapeutics Inc. Phase: 1, 2

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SAKK 18/25 (ORIGIN2): Gemcitabine plus Ivonescimab in Advanced NSCLC Progressing on Immune Checkpoint Inhibitors

Sponsor: Swiss Cancer Institute Phase: 2

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Diagnostic Performance of [68Ga]Ga-HKG301 (FAP-2286) PET/CT in Biologic Borderline Resectable Pancreatic and Invasive Lobular Breast Cancers – FAPTRACE Trial

Sponsor: Gemeinnuetzige Salzburger Landeskliniken Betriebsgesellschaft mbH Phase: 2

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Multicenter, Open-label, Randomized Phase 2 Study of Weekly versus Alternative Ficerafusp Alfa Dosing in Combination with Pembrolizumab for First-line Recurrent or Metastatic HNSCC

Sponsor: Bicara Therapeutics Inc. Phase: 2

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A clinical trial of MK-1568 in participants with prostate cancer (MK-1568-001)

Sponsor: Merck Sharp & Dohme LLC Phase: 1

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PPPTH: Phase II Randomized Trial of Topical Papaverine to Prevent Postoperative Hypoparathyroidism After Total Thyroidectomy

Sponsor: Azienda Provinciale Per I Servizi Sanitari Phase: 2

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VIVALDI: A Pilot Study of the LSD1 Inhibitor Iadademstat in Combination with Azacitidine and Venetoclax in Newly Diagnosed Acute Myelogenous Leukemia Patients with Suboptimal Response to the Standard of Care Treatment.

Sponsor: Grupo Cooperativo De Estudio Y Tratamiento De Las Leucemias Agudas Y Mielodisplasias Phase:

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