6 new oncology trials approved in Europe


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6 new oncology trials approved in Europe

Good morning, here is a concise selection of oncology and haematology trials first authorised in Europe in the last week.

A phase II randomised trial investigating the benefit of adjuvant immunotherapy after neoadjuvant chemoimmunotherapy for resectable NSCLC (ADIL)

Sponsor: Oslo Universitetssykehus HF Phase: Not specified

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A Phase 3 Randomized Study Comparing Ramantamig Plus Daratumumab Versus Investigator’s Choice of Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone (DVRd) or Daratumumab, Lenalidomide, and Dexamethasone (DRd) in Participants With Newly Diagnosed Multiple Myeloma for Whom Hematopoietic Stem Cell Transplant is Not Planned as Initial Therapy.

Sponsor: Janssen Cilag International Phase: Not specified

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Multicenter, open label, phase II clinical trial of inotuzumab ozogamicin as prophylaxis for relapse in patients with high-risk acute B-cell precursor acute lymphoblastic leukaemia after allogeneic stem cell haemotopoietic transplantation

Sponsor: Fundacion PETHEMA Phase: Not specified

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An Open-label, Multi-Center, Single-arm Prospective Clinical Trial to Evaluate Efficacy, Safety, and Pharmacokinetics of Gamunex®-C plus Standard Medical Treatment to Prevent Infections in Participants with Secondary Antibody Deficiency Associated with Chronic Lymphocytic Leukemia, Multiple Myeloma, or Non-Hodgkin Lymphoma (Sigma).

Sponsor: Grifols Therapeutics LLC Phase: Not specified

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Optimization of De-EscalatiON strategies in early breast cancer (ODEON)

Sponsor: Istituto Di Candiolo Fondazione Del Piemonte Per L'Oncologia IRCCS Phase: Not specified

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Randomized phase 2 study of second-line chemotherapy comparing FOLFIRI + ivonescimab versus FOLFIRI + bevacizumab in Microsatellite Stable (MSS)/proficient MisMatch Repair (pMMR) BRAF wild type (wt) advanced colorectal cancer (mCRC) without liver metastases

Sponsor: Unicancer Phase: Not specified

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